Quantitative determination of caffeine in coffee by chemiluminescent method

Authors

  • N. Yu. Bondarenko National University of Pharmacy, Ukraine
  • M. Ye. Blazheyevskiy National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/ubphj.16.33

Keywords:

determination, luminol, hemoglobin, Caffeine, coffee, chemilumeniscence method

Abstract

The method of caffeine chemilumeniscent determination in coffee beans «Arabica» (Galka Ltd, Lviv, Ukraine) based on reaction of inhibition of chemilumeniscent oxidation of luminol by hydrogen peroxide, catalyzed by blood hemoglobin have been elaborated. It was found that other purine compounds including theobromine and theophylline, in comparable amounts relative to caffeine showed no inhibitory activity or any other effect on chemiluminescence parameters of the system. A recovery was 100.13 ± 1.96%, RSD ≤ 2.12% (δ = + 0.14%).

Author Biography

N. Yu. Bondarenko, National University of Pharmacy

кафедра фізичної та колоїдної хімії, доцент

References

Бондаренко Н.Ю. Кількісне визначення кофеїну хемілюмінесцентним методом в лікарських формах / Н. Ю.Бондаренко, М. Є.Блажеєвський // Фармац. журн. – 2005. № 2. – С. 75 – 79.

Ечмаева Т. А. Природа быстрого затухания хемилюминесценции при окислении люминола перекисью водорода / Т. А. Ечмаева, В. М. Бердников // Журн. физ. химии. − 1995. − Т. 69, № 6. – С. 1089−1091.

Федорова О. С. Хемилюминесцентное окисление люминола и механизм разложения Н2О2 в присутствии гомогенных катализаторов / О. С. Федорова, В. М. Бердников // Теор. и эксп. химия. – 1983. − № 3. − С. 334–339.

Chittrakarn S. Quantitative analysis of mitragynine, codeine, caffeine, chlorpheniramine and phenylephrine in a kratom (Mitragyna speciosa Korth.) cocktail using high-performance liquid chromatography / Somsmorn Chittrakarn, Pimpimol Penjamras, Niwat Keawpradub // Forensic Sci. International. – 2012. – V. 217, Is. 1 – 3. – P. 81–86.

Danhelova H. Rapid analysis of caffeine in various coffee samples employing direct analysis in real-time ionization-high-resolution mass spectrometry / Hana Danhelova, Jaromir Hradecky, Sarka Prinosilova et al. // Anal. Bioanal. Chem. – 2012. – V. 403. – P. 2883–2889.

European Pharmacopoeia. Vol. 1-2 / European Directorate for the Quality of Medicines & Health Care. – 7th edition. – Strassbourg : – Council of Europe, 2010. – 3536 p.

Masoum S. Photoluminescence quantitative analysis of gallic acid and caffeine in green tea using multi-way chemometric approaches / S. Masoum, S. Heshmat // Iranian J. of Math. Chem. – 2015. – V. 6, Is. 2. – P. 109–119.

Mnatsakanyan M. The analysis of café espresso using two-dimensional reversed phase–reversed phase high performance liquid chromatography with UV-absorbance and chemiluminescence detection / Mariam Mnatsakanyan, Paul G. Stevenson, Xavier A. Conlan et al. // Talanta. – 2010. – V. 82, Is. 4. – P. 1358–1363.

Tobolkina E. Standard addition strip for quantitative electrostatic spray ionization mass spectrometry analysis: Determination of caffeine in drinks / Elena Tobolkina, Liang Qiao, Christophe Roussel, Hubert H. Girault // Talanta. – 2014. – V. 130, № 1. – P. 377–381.

Wei Y. Voltammetric determination of caffeine at Pt/Carbon nanotubes composite modified glassy carbon electrode / Yingliang Wei, Luping Zhang, Chen Shao et al. // Chem. Anal. – 2009. – V. 54. – P. 607 – 617.

Zhang X. Improvement of near infrared spectroscopic (NIRS) analysis of caffeine in roasted Arabica coffee by variable selection method of stability competitive adaptive reweighted sampling (SCARS) / Xuan Zhang, Wei Lia, Bin Yin et al. // Spectrochim. Acta. – 2013. – V. 114. – P. 350–356.

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Published

2016-06-13

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