The dosage form of biological active complex from chikling vetch anti-inflammatory and analgetic effects investigation

Authors

  • V. A. Volkovoy National University of Pharmacy
  • N. M. Shakhvatova National University of Pharmacy
  • M. Ye. Bereznyakova National University of Pharmacy
  • G. P. Fomina National University of Pharmacy

DOI:

https://doi.org/10.24959/ubphj.17.129

Keywords:

anti-inflammatory, analgesic action, carragenin, fetal acid, medicinal form of BAS complex, with rows of sowing

Abstract

Topicality. In recent years, interest in phytotherapy has grown significantly. In the pharmaceutical market, more and more drugs of plant origin are emerging. The search for biologically active compounds of plant origin is of scientific and practical interest because of the fact that these compounds have a wide spectrum of pharmacological action and low toxicity.
Aim. To investigate the anti-inflammatory and analgesic drugs action of the seedlings with the conventional name “Latiron”.
Materials and methods. Study of the anti-inflammatory effect of “Lariton” on the carragenin edema model on 40 white nonlinear mice and the analgesic activity on the model of acetic acid in 18 white nonlinear rats.
Results and discussion. The results of the experimental study showed that the antiarrhythmic agent of “Latiron” also exhibits a moderate anti-inflammatory effect on carragenin edema, and an analgesic effect on the model of acetic acid in a dose of 40 mg/kg of animal weight.
Conclusions. Thus, the study of the polyvalent action of the dosage form “Latiron” is promising and expedient in the treatment of arrhythmias.

Author Biographies

V. A. Volkovoy, National University of Pharmacy

d. med. s. professor of the Department of Pathological Physiology

N. M. Shakhvatova, National University of Pharmacy

postgraduate student of the Department of Pathological Physiology

M. Ye. Bereznyakova, National University of Pharmacy

d. med. s. professor of the Department of Clinical Laboratory Diagnostics

G. P. Fomina, National University of Pharmacy

cand. med. s. associate professor Department of Clinical Laboratory Diagnostics

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Published

2017-10-17

Issue

Section

Pharmacology and biochemistry