Studying the influence of 2-((4-R-3- (morfolinomethylen)-4H-1,2,4-triazole-5-yl) thio)acetic acid salts on growth and progress of corn sprouts

Authors

DOI:

https://doi.org/10.24959/ubphj.17.93

Keywords:

1, 2, 4-triazole, corn sprouts, Galatea hybrid

Abstract

Topicality. Agricultural industry urgently requires new and effective growth stimulating remedies. 1,2,4-triazole derivatives have had exhibited themselves as active fungicides and growth stimulators and the salts of 2-(4-R-3-R1-1,2,4-triazole-5-yltio)acetic acid are quite promising in this aspect.
Aim. To determine the impact on quality indicators of Galatea hybrid corn sprouts germination after the processing with solutions of 2-((4-R-3 (morfolinomethylen)-4H-1,2,4-triazole-5-yl)thio) acetic acid salts.
Materials and methods. The objects of our research were 10 new substances derivative 1,2,4-triazole derivatives. Further it was studied the impact of these compounds on the performance and germination of the “Galatea” hybrid corn seed in 2016 harvest. We have used auxin as the study comparison and distilled water was used as a control.
Results and discussion. The study had found that these compounds could differently influence on the growth and development of corn sprouts. It was mentioned that on the growth stimulating activity intensiveness can influence the replacement of amino group at the N4 nitrogen atom of 1,2,4-triazole cycle and the type of cation which is combined with acids.
Conclusions. In the result of our experiment it was determined the prospects of further investigations of synthesized compounds as a growth stimulators and noted appropriateness of “structure action” dependences could be integrated into future research.

Author Biographies

R. O. Shcherbyna, Zaporizhzhia State Medical University

C. pharm. s, senior teacher of the toxicological and inorganic chemistry department

O. I. Panasenko, Zaporizhzhia State Medical University

D. pharm. s, professor, head of the toxicological and inorganic chemistry department

Ye. H. Knysh, Zaporizhzhia State Medical University

D. pharm. s, professor, head of the management and pharmacy economics medical and pharmaceutical commodity research department

N. A. Khromykh, Oles’ Honchar Dnipropetrovsk National University

C. biol. s, senior research staffer of the physiology and plant Introduction department

Yu. V. Lykholat, Oles’ Honchar Dnipropetrovsk National University

D. biol. s, professor, head of the physiology and plant Introduction department

References

Шишов, А. Д. Определение ростстимулирующих концентраций новых регуляторов роста и индукторов устойчивости растений / А. Д. Шишов, Г. Л. Матевосян // Фундаментальные исследования. – 2005. – № 9. – С. 46-47.

Щербина, Р. О. Аналіз фармакологічної активності похідних 1,2,4-триазолу / Р. О. Щербина // Фармац. часопис. – 2014. – № 4. – С. 145-150.

Біологічні властивості сполук, що утворені поєднанням 1,2,4-триазолу, фурану та інших функціональних замісників / Д. М. Данільченко, В. В. Парченко, О. І. Панасенко, Є. Г. Книш // Актуальні питання фармац. і мед. науки та практики. – 2015. – № 3. – С. 93-97.

Парченко, В. В. Нові S-похідні 1,2,4-триазолу як потенційні оригінальні вітчизняні ветеринарні лікарські засоби / В. В. Парченко // Фармац. журн. – 2012. – № 3. – С. 43-48.

Дослідження рістстимулюючої активності похідних 1,2,4-триазолу на прикладі насіння соняшника простого / І. І. Аксьонова, Р. О. Щербина, О. І. Панасенко та ін. // УБФЖ. – 2014. – № 6. – С. 78-82.

Пат. 109099 Україна, МПК C 07 D 249/08 (2006.01), C 07 D 249/12 (2006.01), C 07 D 413/06 (2006.01), A 01 N 43/653 (2006.01). Солі S-похідних 1,2,4-триазолів, що стимулюють ріст насіння соняшника / [Е. Г. Книш, О. І. Панасенко, Р. О. Щербина та ін.]. – Заявл.: 27.10.2014. Опубл.: 10.07.2015. – Бюл. № 13.

Пат. 110453 Україна, МПК (2016.01) A 61 K 31/00, C 07 D 249/00. Похідні 1,2,4-триазолів, що стимулюють ріст соняшнику / [Е. Г. Книш, О. І. Панасенко, А. А. Сафонов та ін.]. – Заявл.: 05.04.2016. Опубл.: 10.10.2016. – Бюл. № 19.

Triazole as pharmaceutical potentials / Rakesh Kumar, Mohd. Shahar Yar., Saurabh Chaturvedi et al. // Intern. J. of PharmTech Res. – 2013. – Vol. 5, № 4.– P. 1844-1869.

ДСТУ 4138-2002. Насіння сільськогосподарських культур. Методи визначення якості. Розділ 2.2. «Методи аналізування схожості насіння і енергії проростання». – К.: Держспоживстандарт – Україна, 2003.

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Published

2017-02-17

Issue

No. 1(48) (2017)

Section

Pharmacology and biochemistry

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