Study of the immortelle carbohydrates (Helichrysum bracteatum)




immortelle, free and bound sugars, gas chromatography with a mass spectrometric detector


Topicality. Medicinal plants have great importance for medicines development and production and dietary supplements. Recently there has been a persistent tendency to increase the demand for medicinal plant; therefore, an important direction of scientific study is the expansion the base of herbal drugs of medicinal plants for the pharmaceutical industry.

Aim. To study the qualitative composition and content of sugars using chromatographic methods in herbal drugs of immortelle (Helichrysum braceatum).

Materials and methods. Herbals of immortelle was used for the study. To study the qualitative composition and content of hydrocarbons, the gas chromatography method with a mass spectrometric detector (GC/MS) was applied.

Results and discussion. As a result of the study, 12 sugars were detected in flowers among the bound carbohydrates and among the free – 13 compounds. In the herb it was found among the bound carbohydrates – 10 sugars and among free – 12 compounds. Among the identified free carbohydrates in the flowers of the immortelle are in significant amounts of sugar: sucrose (12.35 mg/g), glucose (10.43 mg/g) and among bound carbohydrates the following sugars: glucose (21.97 mg/g), fucose 21.38 mg/g), arabinose (7.98 mg/g). In the herb of immortelle among the identified free carbohydrates in large quantities there are such sugars as: sucrose (9.08 mg/g), glucose (7.37 m/g), among the bound carbohydrates – the following sugars: xylose (26.84 mg/g), glucose (9.78 mg/g). Other specific sugars are found significantly

Conclusions. At the first time, the determination of the qualitative composition and content of sugars was carried out using chromatographic methods herbal drugs (herb and flowers) of immortelle (Helichrysum braceatum). Significant amounts of sugars are found in flowers among the specific monosaccharides: glucose (32.40 mg/g), fucose (21.38 mg/g) and sucrose (12.35 mg/g), in the herb – xylose (26.84 mg/g) glucose (17.15 mg/g), and sucrose (9.08 mg/g). The experimental data obtained indicate a rather diverse and rich content of sugars the in herbal drugs of immortalle.

Author Biographies

A. M. Moskalenko, National University of Pharmacy

PhD-student of the Department of  Nutriciology and Pharmaceutical Bromatology

N. V. Popova, National University of Pharmacy

Doctor of Pharmaceutical Sciences, Professor, Head of the Department of Nutriciology and Pharmaceutical Bromatology


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Pharmaceutical chemistry and pharmacognosy