The studying of antioxidant activity of salts 2-((4-R-3-(morpholinomethylen)-4H-1,2,4-triazole-5-yl)thio)acetic acids


  • R. O. Shcherbyna Zaporizhzhia State Medical University
  • O. I. Panasenko Zaporizhzhia State Medical University
  • Ye. H. Knysh Zaporizhzhia State Medical University



1, 2, 4-triazole, synthesis, prediction of biological activity


In this work we have conducted the synthesis, the establishment of physical-chemical properties and subsequent Pass-screening of possible biological activity for new alkyl derivatives of 4-R-3-(morfolinometylen)-4H-1,2,4-triazole-5-thioles. According to the results of computer prediction it was found that it is advisable to perform in vivo studies for these substances on the ability to use in the treatment of hastrinomy, ulcers, tuberculosis, atherosclerosis and for eradication of Helicobacter Pylori.

Author Biography

R. O. Shcherbyna, Zaporizhzhia State Medical University

старший викладач кафедри


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Pharmacology and biochemistry