The studying of antioxidant activity of salts 2-((4-R-3-(morpholinomethylen)-4H-1,2,4-triazole-5-yl)thio)acetic acids

R. O. Shcherbyna, O. I. Panasenko, Ye. H. Knysh

Abstract


In this work we have conducted the synthesis, the establishment of physical-chemical properties and subsequent Pass-screening of possible biological activity for new alkyl derivatives of 4-R-3-(morfolinometylen)-4H-1,2,4-triazole-5-thioles. According to the results of computer prediction it was found that it is advisable to perform in vivo studies for these substances on the ability to use in the treatment of hastrinomy, ulcers, tuberculosis, atherosclerosis and for eradication of Helicobacter Pylori.


Keywords


1,2,4-triazole; synthesis; prediction of biological activity

References


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GOST Style Citations






DOI: https://doi.org/10.24959/89551

Abbreviated key title: Ukr. bìofarm. ž.

ISSN 2519-8750 (Online), ISSN 2311-715X (Print)