The therapeutic possibilities of carboxytherapy for psoriasis
DOI:
https://doi.org/10.24959/ubphj.18.192Keywords:
psoriasis, keratinocytes, carboxytherapy, antiproliferative, anti-inflammatory effectAbstract
Topicality. Psoriasis is a chronic autoimmune disease characterized by changes in the growth and differentiation of the epidermis. 2-5 % of the population of the planet have psoriasis, and it is 30 % in the structure of skin diseases. The multifactorial concept of the pathological process in psoriasis determines a wide range of pharmacotherapy of this disease. Modern antipsoriatic agents are not effective enough and have a variety of side effects.
Aim. To summarize the existing scientific literature data conserning the possibility of treating psoriasis with carboxytherapy.
Results and discussion. Carboxytherapy is an important part of the treatment and rehabilitation of patients with psoriasis. The antipsoriatic effect of carboxytherapy is realized through the local and resorptive effect of CO2: antiproliferative, antiinflammatory, antioxidant, antimicrobial, antihypertrophic, reparative and analgesic. Carboxytherapy in psoriasis promotes tissue detoxification, improves immunity, improves tissue trophism, and eliminates venous-interstitial lymphatic stagnation due to hemodynamic, tissue, and biochemical mechanisms of action of CO2.
Conclusions. Carboxytherapy as an additional alternative to pharmacotherapy has a synergistic effect together with formulary therapy, but at the same time reduces the dosage of approved drugs and their side effects.
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