Нydroxycinnamic acids of sea buckthorn





sea buckthorn, hydroxycinnamic acid, РC, TLC and HPLC


Topicality. Medicinal plants are widely used to treat acute and chronic diseases, in addition, it is used as a prophylactic agent. Drugs and dietary supplements are created on their basis. Preparations based on medicinal plants have low toxicity with a sufficiently high efficiency, a wide spectrum of therapeutic action, a complex organ-protective effect, a harmonizing effect on all organs and systems of the body.
Aim. To study the qualitative composition and content of hydroxycinnamic acids in fruits, leaves, bark, oil meal and juice of sea buckthorn varieties Solodka ginka using chromatographic methods.
Materials and methods. The objects of study were fruits, leaves, fruit juice, oil meal and sea buckthorn bark, harvested at the pharmacopoeial garden of the NUPh (2018).
Results and discussion. By means of chromatographic methods, 10 hydroxycinnamic acids were identified in sea buckthorn raw materials. As a result of the analysis, 10 hydroxycinnamic acids were determined: gallic, hydroxyphenylacetic, chlorogenic, caffeic, syringic, coumaric, ferulic, synapic, cinamic and quinic acids. The acid content in μg/g is: quinic 5572.75, cinnamic 656.55, hydroxyphenylacetic 452.53, gallic 342.88, chlorogenic 369.85, ferulic 68.26, coumaric 67.42, syringic 30.90, sinapic 6.27 and caffeiс 38.11.

Conclusions. For all types of herbal drugs quinic acid is dominant. The largest amount of hydroxycinnamic acids is found in sea buckthorn leaves. In this way, herbal drugs of sea buckthorn can be used for creation of medications and biologically active additives based on it for the treatment and prevention of diseases.

Author Biographies

L. S. Naumenko, National University of Pharmacy

postgraduate student of the Department of Chemistry of Natural Compounds and Nutrition

N. V. Popova, National University of Pharmacy

Doctor of Pharmaceutical Sciences, Professor,  Department of Chemistry of Natural Compounds and Nutrition

L. A. Bobrytska, National University of Pharmacy

Doctor of Pharmacy (Dr. habil.), Professor of the Industrial Technology of Drugs Department


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Pharmaceutical chemistry and pharmacognosy